More genes in the human microbiome than stars in the observable universe

A new study revealed millions of genes unique to individual microbiome samples, suggesting the genetic diversity ...

A team of US scientists is embarking on an immense project to catalog all the genes in the collective human microbiome. In the team's first published study an astounding 46 million genes have been chronicled from just 3,500 human microbiome samples. Half of those genes are unique to single human samples.

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CRISPR breakthrough allows scientists to edit multiple genes simultaneously

Genes and proteins in cells interact in many different ways. Each dot represents a gene; the ...

We've seen a number of recent improvements to the CRISPR gene editing method, from enhanced precision to novel techniques to block the process. But despite all these innovations, the technique is generally only able to modify one single gene at a time. An incredible new breakthrough from scientists at ETH Zurich has, for the first time, demonstrated a new CRISPR method that can modify dozens of genes simultaneously, allowing for more large-scale cell reprogramming.

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Incredible Stanford study discovers thousands of novel proteins produced by human microbiome

Researchers have discovered small proteins produced by the human microbiome that have gone undetected due to ...

A remarkable new study from scientists at Stanford University has revealed thousands of previously undiscovered small proteins produced by bacteria in the human microbiome. Almost all of these newly described proteins serve unknown functions in the human body and the researchers suggest their discovery opens up a new frontier for future therapeutic drug development.

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Pharma giant admits data manipulation in FDA application for multi-million-dollar gene therapy

The FDA claims a Novartis subsidiary was aware there was inaccurate data in its application before ...

A newly published statement from the US Food & Drug Administration (FDA) has revealed inaccurate, intentionally manipulated data was included as part of a submission for a major new gene therapy that was approved for public use in May. The FDA alleges AveXis, the company developing the drug, was aware of the data manipulation issue prior to FDA approval but did not notify the regulatory agency until after the product was approved.

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Stem cell map shows how immortal invertebrate regenerates itself

Hydra are tiny freshwater invertebrates that can regenerate any tissue type in their bodies, including their ...

Our bodies do a decent enough job of repairing themselves, able to patch up wounds, fight off infections and even heal broken bones. But that only applies up to a certain point – lose a limb, for example, and it's not coming back short of a prosthesis. Other creatures have mastered this skill though, and now scientists at the University of California Davis (UC Davis) and Harvard have sequenced the RNA transcripts for the immortal hydra and figured out how it manages to do just that.

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Scientists home in on six forms of exercise to best combat obesity genes

In a new study jogging proved to be better at counteracting the effect of any obesity ...

A team of scientists from Taiwan is suggesting not all exercise is equal when it comes to those with a genetic propensity for obesity trying to lose weight. The study concluded jogging was better for weight loss than either swimming or cycling in those subjects with a genetic predisposition for obesity.

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RNA recovered and sequenced from 14,000-year-old mummified wolf

Researchers have successfully sequenced the RNA transcriptome of a 14,300-year-old wolf found frozen in the Siberian ...

Under the right conditions, DNA has been known to last for thousands of years, allowing scientists to study the genomes of ancient Egyptians, the very first Brits, and even early human ancestors. RNA, on the other hand, degrades much more quickly and was thought impossible to recover in older samples. But now researchers have done exactly that, isolating and sequencing the RNA of a 14,000-year-old wolf found frozen in the Siberian permafrost.

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Large veteran study homes in on genetic risk factors for PTSD

Eight genetic regions have been identified as potentially responsible for increasing a person's risk of developing ...

In one of the largest, and most detailed studies of its kind conducted to date, a team of researchers examined data from over 150,000 US war veterans and found eight specific genetic regions that seem to confer an increased risk of developing post-traumatic stress disorder (PTSD).

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